Shrimps continue to be the major foreign exchange earner in the marine sector of India due to heavy demand for export purposes. Shrimp farmers are loosing millions of dollars annually due to the large scale mortality of shrimp due to diseases caused by antibiotic resistance pathogens. The present study were undertaken to isolate the shrimp pathogen, Vibrio parahaemolyticus from the diseased shrimp, Penaeus monodon. Seven herbal plants were selected based on their antibacterial characteristics. In Ethyl alcohol and aqueous solvent extraction maximum inhibition zone were in Punica granatum (24.43 ± 0.15 & 22.60 ± 0.10 mm), ethyl acetate solvent extraction had more effective in Azadirachta indica (12.56 ± 0.15 mm), Dichloro methane solvent extraction maximum inhibition zone were in Curcuma zedoaria (14.86 ± 0.05mm) at 500µg/disc concentration. Punica granatum were showing more effective in zone formation compare with other six herbal plant extracts.
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